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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b4d6a2bc3b68ff440cb4a5bc4ed4072dd3dfd316f6d920f3507ce0472453302' 
  AND token = 'sXqAm/mCn1IJFXvKyAVZgbK09RM1a52REgsEjfXnn2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}