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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2b8abbdf33d181ee8b572083bfc1c6d9c0e37eeba7fdff35c414d3d0ca21ff' 
  AND token = 'V2+ao0ZAtgIBznIiyZyoa8qFUY7iRzBRCC/K4eOc2fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}