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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64684978f360fb5d2b571aad4ad8d7fc1f5c30f06db0eef5f49dd0f107868083' 
  AND token = '12ETuzAQx91oYQpLph2gLsO/5G2LieCW2mThOu6Hm20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}