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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86e4721fbb1e5c6d481283679ae4957a83d2f459d699938d4521c8c76249c0cf' 
  AND token = 'qF4JE1IK1jex3P3/F42PPZyxYpF2AtiVPNv2bFl4zf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}