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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a5881236ecd8a81cd5a61281496e5f4e87b5cd395b767db66f71c3b6f9a3cd' 
  AND token = '5rXU1VqvxDMt7AqyxaQA95snMnqe3iPwsu/uFbz2mu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}