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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3f59fd85d9635eede4676d2d3bf0968dd5a6a262919bb42d1f04d70949c06f' 
  AND token = 'Y0CfrdjB/b3sYoXxcNUZO9v+/uqCONfpJ+iYjFpcmxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}