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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bf06e277cf4e0644849720789cce9ba5b56e57754ec8f87c1a36bcfad44fd57' 
  AND token = 'O1bTLM3TNqRrmB0Hy/eS1mitlfxQ4oyEv53Qrx+zEzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}