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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e0dc93aa558f3d3b7ca5e413e551e18e2abb82ddb6b46f7cf0f6566c2e2547' 
  AND token = 'cEznIEyRvEFVHtYoHPsShS1XKJdukNEpeRHZiLaMGXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}