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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ea7714b1ddf68e4ff5bf29cdc3136d3ee99e4e887d821797b02a53aeccee62' 
  AND token = 'xGIwp8LadEgCcRO2QbaVpMZ7Q4AQWk5yOQD67X6VpF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}