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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c06efb56085d7a54bb3cab1679ee4afa181157f5c1f7dffe930b244ac4c793b' 
  AND token = 'BBO7GL2VmFszsD2hdGUeI8xCbJoJV005LZ1ih2EYxHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}