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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2c628e4044fc2daded694fdcfcf4872d4a2abf8852d1ce06a18cbb05b219bc' 
  AND token = 'C55Pa6gX8a/SMMYNZhoYn8PWLUfDHvVwardFDIJD7y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}