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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949cade82b317df961febfc775b4c560b08d83f277959f8f7580ed569525f1e5' 
  AND token = 'Wzj0uBp48pp1hh3MzLe3W8wF+hT36W8ew6NZMqoeRwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}