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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e41b132c7a9b98ba61c3a4940127794c44e09fdec9da14796c67db3488a1ee' 
  AND token = 'EDzf8b5oU0mODTrBf74iasAMql6RR59khM8pNxmCYlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}