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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ab73dccb7aee215d2dee847ce0259e3ae07701dc7a1e7bc70d071c254f7d08' 
  AND token = 'IvVkCm3JNiqHACEW+RAYjhIh/LJJgxLsQbShzzYHF9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}