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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603a840ba9b14fbf8955b15451e36610444595f3d4c814d7692feb8db7cc94b7' 
  AND token = '8UHJ3Qm9cnUOgTKHeHSW51uYTFsdphJnlbo7cfTF33Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}