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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f2de1d1bc050e4ddc0fde80e6d00e6b778fd525838cc0fa29f747803557510' 
  AND token = 'iAdiK0u+Xo33gx6a/4nnPxg1Yt4PRLC0MUL4nE+ouqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}