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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b2b54925785c51482c06171eda6d221adfc8f797d50e36e93a2638797b69ad9' 
  AND token = 'zfZIPjSh3K9vC+WHIAr+MbGc3T87+JB43GNG6U3AN0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}