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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d0f122e003f7a1cceb18d4803974a54ff75c8b28a1238159159334f8fb83de' 
  AND token = 'dGDUGmSm/hhHuFLVtAFRpS55QxMJrP3Nj0nL5IGQywI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}