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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef595e8aeab854e2f276a7465d8f37398758bd5839b8421ad76b6950e17413b' 
  AND token = 'r03p7Nf/wsQk6p31EypYofqmWPMTZslRATdw5GWUgvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}