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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab5977e0fe013fa62193f0903de27d83214d49feba37e7f9ea1e9f23d2fd72d' 
  AND token = '1Z5tyLCWFWqcp32a9LqHbPQhpEvU0zbgpxt4v0DgNJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}