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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc7a77cefb3db1354d065611c40b6879891c8cdb6b5ab8e00d705da11415cdd2' 
  AND token = 'Bqz1os+ruN9GS0LFnx8eVPsMZb6iegpc/NJUb+C7Rg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}