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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5bc55a2aa2b1015140cba7fb5476bcda3adfc754b398713bbe2c742e5f557a' 
  AND token = 'Zme2is//q/Bz3q0pdgX9y/usmCmzGZRJhnnUNa7Vxkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}