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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f42d5d217db1274e0faf81035bff726ae1fc5968796ad23265618ec73ae8d7f2' 
  AND token = 'owiy9cVImBCQa459uopI+lPLk39J+RCyytNXY746Kek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}