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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0047264a1143d9480315e0c3cac051707a79e8075f425cdc2e00c90d9e69a1f' 
  AND token = 's5lbyJRoCO8Vp+pXYFS80fLbjKT01pFOgpUVmaS//g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}