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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba10b1785c999a2d1139e90791215e14170749da4477c905d897253200a7352' 
  AND token = 'J8yQM8DgTQLGjBLhy+n+t1QfHhDy9N+juhXr3vrBwjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}