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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346daec1f1b37cad4ef354aba0311a5cfaeea3bf37ff60bf29702f3b91ffb728' 
  AND token = 'sq0b60kKG9waAW6CirtKRvCZ0XqrlQfRtR8cOA5RyD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}