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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db19d25ffdc302e6f932a2ed55ad86051b0bafefe1c7445c8a355380de4e828' 
  AND token = 'w25pRsfx76CHfHugS0/VKH9tQC9hYGBTTZnelPfc0u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}