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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860b4bb28715a62671a01339410899395a6e3e34a0ea9d1f41f790598516e32c' 
  AND token = '8k+SoL4ub/XK7gsfrUlUDenSQu8zjiYHSZDKIV0OOdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}