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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48714090656e1bcd9d5c2beee140209446c928eff033e20b269080201dd6fbb' 
  AND token = 'o+1R0CnsXPyCvia2cRouv4Jd+Qtn7d2ROZXfpdHBIz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}