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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2a87ca27fd05a08ec65ae544c2d10b86e4c694e27628ca164e5c8338f4d057' 
  AND token = 'wy987181OrlINgw32K7wIdTTCvOqilgrSjpqHrIzF9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}