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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e559f059c686f1565c0a01303006828d3dc750e1103b801dbed1e7e68e3009' 
  AND token = 'e+YZ0Ysgzi+Gj4XlEG36gkyDSa1/cknKVjGfvIT0OMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}