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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a748cd8837514bb50ecfbcffc2f2b34826e50fc7c05b016db81c8bdacd8488' 
  AND token = 'Fs2KqvcYNd2RGnwfEC5+Neo3obR/oc7Au+4+VcSGKas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}