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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4145e28bad50e9f6775f3612835e68d0af98609c6942ea61701647105d7d65b3' 
  AND token = 'EIBuGIs9C4KyRtWAj8v3Mdy48v4f8GkR/mjvZHg/U+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}