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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4954a91247c0fe7ebb383628b3f58031e6e20bf002bedeb975fa6bed8b1331fb' 
  AND token = 'ilcGitk3eQI00G4kJablKH5/20VNW6V4k2aVAzImcO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}