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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51046194ed54be375e544433251668bea3499b23bc88472aba5d1f38e7b3a10e' 
  AND token = 'KntpCkfYQ/iS3hM7Hlr8SRV6gG5mCTBIUZIIDezdaWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}