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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1def45240efbcef0c59808ed3e0035090a81bc3a817251b39c10d495b72a19b2' 
  AND token = '21q6/b3YIMrzHv/b9YH+DYOadT7V8IZa3exU8GNhaBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}