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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b675f4651a1261e456dd6ebd848ddd7384a8256cd56165445b6a2fde0f2f981' 
  AND token = '5FGYuLT2e0usHyWE+x6EEYtxLV1InWuVuzVzm08ZDmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}