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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2209b4f281e94df855328f4c7fdba419fd3d3db011cd0a709e600b278c32c5e' 
  AND token = 'YDYYj2lg4skss4kMUaMyUEJNWzk4Vxm2EEoSHJ4V4CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}