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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66533800e8e4571f1cd65ab8e01b107ff36916c72700c290d9675c0b96384a59' 
  AND token = 'yCSzn799DzKn0G5is011YWr/cWV6P/pOh7xTMyVCKBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}