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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0afc6051f1f29f760ceda722b24f142d27906780bc8be910445c4cd7ae23306' 
  AND token = 'Gc9C0Lc/Psyun9pRHO4R1GWWO4mp2VJndwirHZP9Dq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}