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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08c12ce03aeaddbdd3c07121b42a305f2fc632e111f0014552e36bbf2741afd' 
  AND token = '8JFxpe6VfFaG+zPvUcKSKD5vM3eikDGvxvB6YwmuuD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}