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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf32cb5d86e614fb21901344f9e264848d868ea593676fd7602b7a223711989c' 
  AND token = 'vl2EJ0I5UUYHWyT3TVx1pmH0abpLTbgb2zzlyMVhIUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}