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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bb2426458d30ee39d71daf662d93943fb7a35071fbed0881af296dd0cb1bef' 
  AND token = '2WepVh7I9VvFOXgV9isQpAHNI1owHmJOyb9n80mLLeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}