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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59acacd446c06e28ea3e4e0d55eb6f5bd91c8a5566d9d970b19ac24afe790f2a' 
  AND token = 'K3TfeQXcN/T8Rucza/YRy9iLeyqf7ftzwhUsW0AEr7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}