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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de20a7d600e310ed4786ee732337daf714f71cbdfa77ef79a2c466e8bb11d82' 
  AND token = '06KYi8v0MAn9C02W/KeBwiC/oc8Y6TIdZ1J9ypqfLN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}