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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d9bffce5bef3eb3c1090b53e6f0c08e5148b56483400706ea62c3d37a30b84' 
  AND token = '34BPtz+EjiOnlMsnKI+7rcZDJO0hEjmgIYDcP2bVcYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}