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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549a49ddbb98e282559ed4e445b67b30a4e84ad838c1dd0433decd934097085c' 
  AND token = 'juZH/8v9/w78jmb7BVCkS4vdq1c2XR/+7UDChp/r9u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}