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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04c908911057ab6c69cc6dfe8729fa8f89018a6b24bf46826d2935e1f24f330' 
  AND token = 'PETYS4bhUnNLgUyNCf18t7r42hRG/FMY7/zqNI3xlbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}