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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6436457cd97c36a58406f4d5076895a0c5d1f8b3f2160f1a091bb523c714bd' 
  AND token = 'DvbK75QzrGkhsGKY53nEPQrmJBO2n51mCz6NCA/3IkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}