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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185dbc7eb3c81f2d003716e3ab16fd58c2c8dfc4bb06bc84b4174caece7cc3b1' 
  AND token = 'LzwC3t4xzkCVoFmC3V08TBmMt0hXvisGKmK1nDdS5E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}